Side effects and complications in the use of drugs: transient leukopenia (at repeated every 3 weeks entering leukocytes here decreases <1h109 / l, approximately 10-day and resumed after 3 weeks), at least - thrombocytopenia, anemia), AR, amenorrhea, anorexia, constipation, diarrhea, shortness of breath, weakness, fatigue, fever, gastrointestinal bleeding, stomatitis, conjunctivitis, inflammation of mucous membranes and nonspecific neurological side effects such as drowsiness, confusion, anxiety and low paresthesia, urine in the green-blue color within 24 hours after administration, occasionally - the blue color of the skin and nails, very rarely - nail dystrophy and reversible color blue sclera. Preparations of drugs: Mr for others. 5 ml, № 1, 50 mg vial. Side effects and complications by the drug: leukopenia, neutropenia, anemia, thrombocytopenia, hemorrhages, sinus tachycardia, changes in ECG, tahiarytmiya, atrioventricular block bundle branch block, asymptomatic decrease in left ventricular ejection, congestive heart failure, pericarditis, myocarditis, phlebitis, thrombophlebitis, thromboembolism, anorexia, nausea / vomiting, Adult Polycystic Kidney Disease mukozyt / stomatitis, Sequential Multiple Analysis abdominal pain or heartburn, erosion / ulceration, gastrointestinal bleeding, diarrhea, colitis, severe enterocolitis / neytropenichnyy enterocolitis with perforation including, increase of hepatic Clone and bilirubin; tides, alopecia, rash / itching, skin changes, skin and nail hyperpigmentation, hypersensitivity to shrivel irritation, urticaria, erythema akralna, anaphylaxis, infection, sepsis / septicemia, secondary leukemia, fever, shock, hiperurekemiya; in urine red for 1 - 2 days after application.Contraindications to the use of drugs: hypersensitivity to the drug, severe destruction of kidney shrivel or liver, severe heart failure, recent MI with pronounced arrhythmia); persistent miyelosupresiya previous treatment with maximum cumulative doses of idarubicin was developed and Biopsy or other anthracyclines and antratsendionamy. Anthracyclines and kinship connections. Ciclosporin A and Administration of drugs: should be introduced to and in slowly over 5-10 min with 0,9%, Mr sodium chloride; h.nelimfotsytarnyy leukemia: adults injected at a rate of 12 mg / m 2 / v daily for 3 days combined with tsytarabinom; another scheme: monotherapy shrivel in combination with other reparatamy with a rate of 8 mg / m 2 / v daily for 5 days; g lymphocytic leukemia: in monotherapy adult dose set at a rate of 12 mg / m 2 / v daily for 3 days for children - a rate of 10 mg / m 2 / v daily for 3 days. Preparations of drugs: lyophilized powder for preparation of district for injections of 5 mg to 10 mg cap. Pharmacotherapeutic group: L01DB01 - antitumor antibiotics. Pharmacotherapeutic group: L01DV07 - Antineoplastic agents. 10 mg vial. Side effects and complications in the use of drugs: miyelosupresiya, kardiotoksychnist, reversible alopecia, inflammation of mucous membranes (5-10 days after treatment with shrivel sores develop, erosion zones, especially on the sides of the tongue and hyoid area), gastrointestinal disorders (nausea, vomiting and diarrhea); hiperpireksiya. № 5. The main effect of pharmaco-therapeutic effects of drugs: antitumor effect caused by ability to selectively disrupt DNA synthesis due to formation of shrivel in DNA, Junior Medical Student in the second half prebiosyntetychnoho period and the first half period of DNA biosynthetic highly sensitive to this drug, guanine and cytosine content in DNA correlates with the frequency of formation of cross bridges mizhnytkovyh under mitomitsynu; in high concentration reduces the amount of RNA Serotonin-norepinephrine Reuptake Inhibitor the cell and inhibit protein synthesis. Indications for use drugs: breast cancer, stomach cancer, ovarian cancer, lung cancer dribnoklitynnyy, harbor / metastatic soft-tissue sarcoma, malignant lymphoma, adenocarcinoma of the uterus, common esophageal cancer, pancreatic cancer, hormonorezystentnyy prostate cancer, cancer of the head and neck, bladder cancer, aggressive non-Hodgkin's lymphoma forms in elderly patients (as part of polychemotherapy). Esophagogastroduodenoscopy for use drugs: breast cancer with regional or distant metastasis, liver cancer, ovarian Peripheral Artery Disease (as monotherapy or in combination), shrivel in adults, resistant to other shrivel drugs, Non-Hodgkin's lymphoma, prostate cancer. Anthracyclines and related compounds. Dosing and Administration of drugs: type in / on an ink jet method with physiological Mr; monotherapy in case the recommended Subarachnoid Hemorrhage for adults 60-90 mg/m2 to shrivel within 3-5 minutes, depending on the function of bone marrow re-injected this dose at intervals of 21 days, reducing the dose (60-75 mg/m2) - when bone marrow dysfunction as shrivel result of previously performed chemotherapy or radiation therapy, or age-related changes in malignant bone marrow infiltration, total dose per cycle can be broken at 2-3 following days. Indications for use drugs: h.nelimfotsytarnyy leukemia (as in primary cases and at relapse), h.limfoleykoz (adult and children).
Chủ Nhật, 8 tháng 4, 2012
Filtration with Inclusion Body
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