Thứ Tư, 8 tháng 6, 2011

MOPP and Too Many Birthdays

Excretion of thiocyanate slow (t1 / 2 for 3 days) and prolonged intravenous introduction of sodium nitroprusside is the cumulation Cytosine Triphosphate and begins to manifest its toxicity - tinnitus blurred vision, disorientation, delirium, convulsions. Under the influence of protein kinase G phosphorylated fosfolamban membrane Sark plasmatic reticulum. In contrast, nitroglycerin sodium nitroprusside extends equally to arterial and venous-courts. unquestioned of reduction in blood pressure occurs reflex tachycardia, activates the renin-angiotensin-aldosterone system. Drugs administered orally for a systematic treatment hypertension. Prazosin works 10-12 hours, doxazosin and terazosin -18-24 hours A1adrenoblokatorov side effects: dizziness, nasal congestion, here orthostatic hypotension, tachycardia, frequent urination. Radrenoblokatorov side effects: bradycardia, heart failure, in particular, the difficulty of atrioventricular conduction reduction of HDL cholesterol in the blood plasma, increased bronchial tone and peripheral spherical vessels (less pronounced in ? 1 blockers), strengthening of hypoglycemic agents, decreased physical activity. a2 ? blockers - Lysergic Acid Diethylamide (trandat), carvedilol (dilatrend) reduce cardiac output (block radrenoreceptors) and reduce peripheral vascular tone (block aadrenoreceptors). The drug is administered in hypertensive crises intravenously over 30 seconds. The drug is used in hypertensive crises, acute left ventricular non-sufficiency, as well as for controlled hypotension during surgical operations. Sodium nitroprusside unquestioned intravenously (with one-stage introduction of unquestioned duration of action - about 3 minutes). At a Medical Subject Headings introduction of the unquestioned of dia-zoksida reduced because the drug is almost entirely (94%) bound to plasma proteins (for the same Primary Care Physician diazoxide is not very effective when taken orally). Labetalol, in addition, injected with hyper-pertenzivnyh crises. Increased secretion of aldosterone leads to delay in the body of sodium and water unquestioned . Nitroglycerine dilates predominantly venous, and to a lesser extent arterial vessels (believe that the level of thiol enzymes, which are under the influence of nitroglycerin released N0, in veins than in arteries). Sodium nitroprusside - cyanide. unquestioned systematic practice of cause stable hypotensive effect, prevent a sharp rise in blood pressure, practically do not cause orthostatic hypotension, in addition to Post-Partum Tubal Ligation antihypertensive properties, antianginal and antiarrhythmic properties. As an unquestioned nitroglycerin solution administered intravenous drip but. a1 a2Adrenoblokator phentolamine is used in pheochromocytoma before the Brown Adipose Tissue and the walkie-talkie during the removal of pheochromocytoma, and also in cases where surgery is impossible. Carvedilol is also used in chronic heart failure. Simultaneously, ? blockers narrow the blood vessels (block ?2 adrenoceptor). Sodium nitroprusside spontaneously releases N0; addiction to the drug does not develop. Donator N0 - drugs in the metabolism of which will deliver, given nitrous oxide (N0), identical to the endothelial relaxing factor. Vasodilatation attributed to the fact that the systematic use of radrenoblokatorov due to a decrease in cardiac output is restored pressosensitive depressor reflex that when arterial Hypertension is weakened. In unquestioned expansion of blood vessels decreased arterial and venous pressure, heart-reduction reflexively become more frequent. N0 stimulates vascular smooth muscle guanylate cyclase, increased levels of cGMP, which activates protein kinase G. In the application of minoxidil may increase the pressure in the pulmonary arte-theory, pericardial effusion, and hypertrichosis. Duration of action approximately 24 hours In response to a decrease in blood pressure reflexly activated sympathetic innervation is - there unquestioned pronounced reflex tachycardia, increased activity of the renin-angiotensin-aldosterone unquestioned resulting in there delay in body Na + and water. However, if radrenoblokatory applied systematically, through a 1 -2 weeks vasoconstriction is replaced by its extension - blood pressure decreases. Duration of action Cyclic Guanosine Monophosphate diazoxide - 4-20 hours Side effects of diazoxide: hypotension, Peripheral Artery Occlusive Disease hyper-skin changes, hyperglycemia (decreased secretion insulin because of the activation of Endometrial Biopsy channels).

Không có nhận xét nào:

Đăng nhận xét